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Post: Preparation of the mobile phase (Topic#4331)

Corrine
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Posts: 12

04-14-10 07:46 PM - Post#5649

Hello all,

I have a question about the solvent used to preparation of the mobile phase for HPLC test. We use purified water passed through 0.45um membrane as the solvent. However, a inspector said it was not allowed to use. We must use ultrapure water. But I didn't find this requirement in the USP.

SO I want to know if it is necessary to use ultrapure water as the solvent in HPLC test.

Thank you very much.

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